Over Hayat
- Programming: Python, R, RMarkdown, Bash, Snakemake, Nextflow
- Version Control: Git, GitLab
- HPC Computing: Sun Grid Engine (SGE), SLURM, access to Scaleway computing infrastructure
- NGS Data Analysis: DNA-Seq, RNA-Seq, Tn-Seq, 16S, metagenomics, sequence alignment, SNP analysis, phylogeny
- Proteomics: Mass spectrometry, Olink
- Functional Analysis: Pathway enrichment, HMM models, Gene Ontology, GSEA
- Statistical Analysis: Alpha & beta diversity, rarefaction curves, DESeq2, Limma, DPGP, Random Forest.
Frans
Tweetalig / moedertaal
Engels
Tweetalig / moedertaal
Arabisch
Tweetalig / moedertaal
Werkervaring
- BIOASTERBioinformaticianBIOTECHNOLOGIEapril 2021 - november 2025 (4 jaren en 7 maanden)Lyon, FranceDevelopment and maintenance of bioinformatics workflows using Nextflow, Snakemake, Python, R, and Bash.Transcriptomics, metagenomics, and proteomics data analysis, from raw data quality control to statistical and biological interpretation, performed on HPC clusters using SLURM and Sun Grid Engine.Development of an automated workflow generating a final HTML report for each project, providing clear and actionable results, including publication-ready figures and tables.Expertise in projects related to the human microbiome, biomarker discovery for drug development, and vaccine research.Involved throughout the entire project lifecycle, from requirement definition and methodological design to analysis execution and presentation of results to clients.
- DOE Joint Genome InstituteMissionseptember 2019 - december 2019 (3 maanden)Berkley, Verenigde StatenDevelopment and application of HMM models for gene identification and classification across 656 fungal genomesPhylogenetic analysis to group identified genes into four functional clades and predict the type of catalyzed cyclizationIdentification of specific amino acid motifs to improve the accuracy of functional predictionsMining and annotation of large genomic databases, integrating sequence and phylogenetic information
- Institut national de recherche pour l'agriculturePhDBIOTECHNOLOGIEjanuari 2018 - april 2021 (3 jaren en 3 maanden)Marseille, FrankrijkComparative analysis of fungal genomes (~1,000 genomes):Identification of gene families, analysis of gene family expansions, phylogenetic reconstruction, and investigation of evolutionary trajectories.Large-scale functional analyses to characterize enzymatic repertoires involved in lignocellulose degradation, combining genome annotation, sequence comparison, and exploration of genetic diversity.Development of a dedicated tool for automated enzyme identification, applied to the analysis of 1,420 fungal genomes and the detection of more than 11,000 candidate genes.
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Opleidingen
- PhDINRAE2021PhD en genomiques des champignons
- Master in bioinformaticsUniversité de Nantes2017Master in bioinformatics/Biostatistics